This site provides brain tissue templates for quantitative neuroimaging research. These templates provide realistic anatomical models that can be used to synthesize phantom images. Phantom images can be developed to simulate a multitude of axial brain images both within a modality (e.g. T1W, T2W, and PDW for MRI) and across imaging modalities (PET, CT, MRI). Downloadable templates are available for nine different slice locations equally spaced across the cerebrum (Fig 1). These slices are sufficient to model approximately one-half of the cerebrum's volume. Brain phantoms developed with these the templates can be used to validate and/or optimize a wide range of quantitative studies in medical imaging. They were initially used to evaluate the accuracy of a "Fuzzy Classifier" method for measurement of grey matter and white matter volumes (Herndon et al., JMRI 1996; 6:425-435).
Guidelines for Phantom Development:
Step 1 - Create region-of-interest (ROI) outlines for WM, GM, and CSF (fat not modeled) from binary templates;
Step 2 - Fill each ROI with pixel values representative of each tissue;
Step 3 -Volume average in the x, y, and z directions.
Sections - Downloading instructions
Web page Design by Gita